Coenzyme Q3, Methyltransferase (COQ3) (Middle Region) Peptide
COQ3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5673885
Quick Overview for Coenzyme Q3, Methyltransferase (COQ3) (Middle Region) Peptide (ABIN5673885)
Target
COQ3
(Coenzyme Q3, Methyltransferase (COQ3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- YALGIVFSEQ IASIVPKGTH TWEKFVSPET LESILESNGL SVQTVVGMLY
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti- COQ3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
-
Background
-
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes. This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Alias Symbols: DHHBMT, bA9819.1, DHHBMTASE, UG0215E05
Protein Size: 369 -
Gene ID
- 51805
-
NCBI Accession
- NM_017421, NP_059117
-
UniProt
- Q9NZJ6
Target
-
You are here:
